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REVIEW PAPER Post-herpetic neuralgia: currently available oral and topical medications in the management of pain a review More details Hide details 1 Clinical Department of Internal Medicine, 4th Military Clinical Hospital, Wrocaw, Poland 2 Clinical Department of Endocrinology, Metabolic and Internal Medicine, University Clinical Hospital, Pozna Poland 3 Internal Medicine Department, Rear Admiral Professor Wiesaw asiski 7th Military Navy Hospital, Gdask, Poland 4 SPZOZ of the Ministry of Internal Affairs and Administration, Department of Internal Medicine and Geriatrics, Krakow, Poland 5 Department of Clinical Oncology, PCK Maritime Hospital, Gdynia, Poland 6 Department of Gastroenterology and Internal Medicine, Autonomous Public Provincial Polyclinical Hospital, Szczecin, Poland Corresponding author Damian Bben 4th Military Clinical Hospital, Clinical Department of Internal Medicine, Weigla 5 Street, 53-114, Wrocaw, Poland J Pre Clin Clin Res

7 Conclusions Mitochondria in PACs should be viewed as an inter-organellar hub that integrates Ca 2+ signaling, bioenergetics, redox control, organelle quality control, and inflammatory signaling through dynamic contacts with the ER, lysosomes/autophagosomes, peroxisomes, lipid droplets, the cytoskeleton, plasma membrane, nucleus, and secretory compartment