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Guri Y, Colombi M, Dazert E, Hindupur SK, Roszik J, Moes S, et al

Histone acetyltransferase inhibition reverses opacity in rat galactose-induced cataract

Notably, under BSO treatment, these molecules may increase cysteine availability but should not restore GSH levels, as BSO irreversibly inhibits -glutamylcysteine synthetase (-GCS) the enzyme responsible for GSH synthesis downstream of cysteine 48