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However, a meta-analysis reported that the use of NAC showed no significant improvement in pregnancy rate, serum LH level, fasting insulin, and LH/follicle-stimulating hormone (FSH) ratio despite that the BMI and total testosterone were significantly reduced (138)

Pharmacologic inhibitors of SLC7A11 effectively induce tumor regression and abrogate MCU-driven metastasis in PDAC (Wang et al., 2022)

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Safety monitoring is also crucial while probiotics and FMT have been safe in trials so far, there is a theoretical risk of introducing infections or causing undesired immune reactions, especially in patients with immune dysfunction (like those on MS immunosuppressants)

Ha, C., Ullman, T