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An oxidation pathway, in which jasmonoyl-isoleucine is oxidized by cytochrome P450 enzymes, mainly CYP94 isoforms, to a 12-hydroxy metabolite and then further via a 12aldehydo intermediate to dicarboxy-jasmonoyl-isoleucine, together with deconjugation by amidohydrolases, is now recognized as a major route for catabolism and deactivation of the hormone, although the hydroxy intermediate can itself cause weak and sustainable expression of certain JA-responsive genes until further oxidation occurs

J Hepatol 58(1):119125

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1,2 This is frequently because of food selectivity and food refusal, need for food to be given in specific presentations and/or textures, preference for certain food groups, and atypical sensory processing

Often referred to as the telomere peptide or longevity peptide, Epitalon has been studied for its potential ability to activate telomerase, support cellular repair, improve sleep quality, enhance immune function, and promote healthy aging