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Key takeaway: Beyond fat burning, AOD-9604 may have broader metabolic effects

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Stretch-induced activation of Ca 2+ -permeable ion channels is involved in the volume regulation of hypotonically swollen epithelial cells

flavone glycoside) The first focused review in 2025 positions prunin as emerging anticancer candidate that modulates cell cycle and apoptosis pathways, with early evidence for combination use and nanoformulations to overcome solubility/bioavailability limits (Rana and Mumtaz, 2025)