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The efficacy of zinc supplementation in treating AD remains controversial, with some studies suggesting no significant benefit, while others indicate potential therapeutic effects (182)

BettiniSBoutet-RobinetECartierCComraCGaultierEDupuyJet al

Cc chuyn gia ti Dr Lacir chng minh rng, sau mt liu trnh s dng, vin ung Glutathione 600 Dr Lacir c th ci thin 70-80% vn v nm v 60% vn v tn nhang

Figure 1 Iron metabolism At present, the exact molecular mechanism of iron overload leading to heart damage is mainly considered to be ferroptosis ( 2+ uniporter, which is essential in causing mitochondrial dysfunction and ferroptosis in cardiac iron overload ( Hepcidin, a peptide hormone originated from the liver, regulates iron absorption and distribution by suppressing the activity of transferrin ( The therapy targeting the hepcidin-transferrin axis has demonstrated initial potential, capable of effectively alleviating iron overload and ineffective erythropoiesis

Aspray TJ, Prentice A, Cole TJ, et al