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However, apCAFs lack the co-stimulatory molecules required to induce T cell proliferation

Human studies show its marked anti-ulcer effects and utility in the treatment of inflammatory bowel disease [2, 4, 33]

2023 Update: The U.S

IFN- is responsible for macrophage activation, enhanced antigen presentation, and induction of nitric oxide-mediated killing mechanisms (Cavalcanti et al., 2012)