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Thareja, Natural products in the 21 st century: revolutionizing therapeutics with flavonoids as key phytometabolites

mansoni can produce prostaglandin E2 (PGE 2 ), while also producing an E/S product of less than 30 kDa in size that can upregulate the production PGE 2 and IL-10 from human keratinocytes

Choline levels can be increased by supplementing with the compound alpha-glycerylphosphorylcholine (GPC)

Nature reviews Neurology 11(8):457470

J Biol Chem 291:68136830 Gaillard PJ, Kerklaan BM, Aftimos P, Altintas S, Jager A, Gladdines W, Lonnqvist F, Soetekouw P, Verheul H, Awada A et al (2014) Abstract CT216: Phase I dose escalating study of 2B3-101, glutathione PEGylated liposomal doxorubicin, in patients with solid tumors and brain metastases or recurrent malignant glioma