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Description

Collectively, these in vivo studies demonstrate the important role of Set7/9 in the development of ROS-associated pathological conditions

These results were confirmed using PY-GC MS data

Moreover, two fusion proteins Gsh2-Gsh1 and Pro1-GshB were constructed to increase the two-step coupling efficiency of GSH synthesis by mimicking the native domain fusion of GshF

Pol Arch Intern Med 132 (4), 1625016250 (2022)

Importantly, results obtained from knockout mice suggests that xCT inhibition could have the least off-side effect in comparison with the GPx4 and GCL (64, 65)