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Jun 2020;47(6):592-600

This reduction in melanin leads to lighter skin tone over time, though many wonder if its possible to reduce skin melanin permanently through such treatments

Variant nomenclature follows the HGVS guidelines ( All variants were checked with Mutalyzer software ( and submitted to the EDS Variant Database ( A unique identifier was obtained for each proband following submission to the EDS Variant Database and is included in the text