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Investigations have revealed that the TNF- blocker infliximab has a certain effect on bone metabolism

Peter Paul de Deyn for access to the human brain materials (NeuroBiobank)

This leads to destabilisation of ionic gradients and subsequent water influx and membrane rupture (Ding et al

JAMA 2008

This mixture was left on ice for 5 min before addition of neutralization buffer (final concentration, 0.17 mM ammonium carbonate (5330050050) in LCMS-grade H 2 O) and gently mixed before being incubated on dry ice for 15 min