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However, a lack of organelles, especially mitochondria, limits the cell death machinery of mature erythrocytes and their ability to undergo specific, regulated cell death modes

The reliance on natural sunlight and specific temperature requirements restricts commercial Spirulina production in open ponds to tropical and subtropical regions, limiting wider global production and potentially increasing transportation costs

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doi: 10.1210/jcem-73-2-307 51 BhatVBMadyasthaKM