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Description

Opa1-overexpressing mice exhibited longer and more tightly packed cristae in the mitochondria of the heart and other organs, and this mitochondrial structure protected the mice from ischemic damage and muscular atrophy

Clarke SJ, Abratt R, Goedhals L, Boyer MJ, Millward MJ, Ackland SP

On the other hand, mitochondrial autophagy, as a means for cells to deal with stress, may contribute to cell survival

Currently, it has been reported that multiple regulatory mechanisms of ferroptosis mediate neuronal death, including iron overload, OS and neuro-inflammation