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Therefore, we combined si-GPX3s with isosilybin B, which plays a pro-apoptotic role by blocking the G1 phase [46], to detect the level of apoptosis

In this regard, SGLT2 inhibitors might prevent cells exposure to oxidative stress and promote cellular repair via up-regulating energy deprivation sensors such as AMPK and SIRT1, as well as via inhibition of insulin/IGF-1 signaling [28]

The impact of KD on mitochondria Research increasingly suggests that mitochondria, key organelles responsible for cellular energy production, play a significant role in the pathophysiology of PD

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