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The deficiency of this essential nutrient has been shown to disrupt the delicate balance of one-carbon metabolism, leading to aberrant DNA methylation and synthesis, ultimately culminating in neural tube defects

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Given that gut microbiota regulate immune function and inflammation, both key features of PTSD pathophysiology, this axis represents a promising therapeutic target

However, it is well known that mitochondrial and cytosolic GSH levels are decoupled during cell death and many other biological processes 40

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