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hi I find it very easy to reach either arm but admit people do ask me that,I cant see why it would be a problem I just sit on end of bed with stuff all laid out on a clean towel and sharps bin handy,draw up b12 with a red filter needle,personal preference here,then discard and do the injecting with the orange needle , if the b12 is cold or you do have a bead of it on injecting needle then yes your right it can sting but again that is a rarity for me