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The distinctive clinical manifestations and singular pathophysiological mechanisms underpinning AD, PD, ALS, and MS engender unique profiles of BBB dysfunction tailored to each disorder

Finally, transfected neurons were immunostained for presynaptic markers, VGLUT1 and synapsin, and postsynaptic marker, PSD-95, to assess functional synapse formation

GantoisIKhoutorskyAPopicJAguilar-VallesAFreemantleECaoRet al

Patients and providers should treat them as directional rather than definitive, and decisions about participating in trials or accessing investigational therapies should always involve a specialist in endocrinology or metabolic medicine

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