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10.1016/j.reprotox.2022.12.002 279 ZhaoY

www.nejm.org/doi/full/10.1056/NEJMoa2500969

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Combined with reduced intrinsic factor, makes deficiency progressively more common over 60

The cellular diversity within ovarian follicles, including oocytes, granulosa cells, cumulus cells, and theca cells, makes single-cell approaches particularly valuable for identifying cell-type-specific biomarkers and understanding developmental trajectories [23, 25]