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Patients were identified with suspected AATD (1 inpatient or 2 outpatient ICD-9/10-CM AATD codes 90 days apart, serum AAT 1.5 and a q-value 18%), no recommendation has been published to date for its use during follow-up

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Preparation of GSH standard solution Mix 100 l of 200 mol/l GSH standard solution and 300 l of 0.5% SSA solution in a microtube to prepare a 50 mol/GSH standard solution

While SOD2 converts superoxide radicals to H 2 O 2 , the deficiency in downstream H 2 O 2 -detoxifying enzymes (CAT and peroxiredoxins) potentially leads to H 2 O 2 accumulation, exacerbating oxidative stress (Chen et al., 2008)