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10.1016/j.expneurol.2010.05.017 121 WakabayashiK.TanjiK.MoriF.TakahashiH

In addition, the levels of Salicylic acid (SA) and Jasmonic acid (JA) increased significantly, the expression levels of the genes encoding transcription factor TGA (PG2023696), pathogenesis-related protein 1 (PR1) (PG0005111), and the transcription inhibitor Aux/IAA (PG0006093) all increased while the expression levels of jasmonate ZIM domain-containing protein (JAZ) (PG0004367), auxin influx carrier (AUX) (PG0006550) and auxin response factor (ARF) (PG0005794) all decreased

This can alleviate the disturbances of suppressing of PI3K/Akt1 and PPAR- pathways, the imbalance of the sex hormone profile, hyperglycemia, dyslipidemia, IR, increased profibrotic factors, and abnormal ovarian histopathological changes in the ovaries of the PCOS model by attenuating ER stress [165]