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Ethics declarations Ethics approval and consent to participate The study was approved by the Hospital 12 de Octubre Ethical Committee (21/580), and all patients and donors provided written informed consent following the Declaration of Helsinki

dahliae from cotton can be divided into defoliating pathotypes, such as strain T-1 (later renamed T9), and nondefoliating pathotypes, such as strain SS-4 2

Specifically, cardiovascular risk factors may mediate at least a part of their effects on the heart and blood vessels via hyperuricemia and the latter may exert their deleterious effects on cardiac and vascular structures via cardiovascular risk factors (notably arterial hypertension)

On the average, our patients seem to get the best benefits in the first 6 9 months of treatment

This precision approach eliminates the temptation to stack medicationsyour personalized single agent is more effective