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Crosstalk between cystine and glutathione is critical for the regulation of amino acid signaling pathways and ferroptosis

A growing body of preclinical research suggests that targeting the ferroptosis regulatory pathway centered on GPX4, including drug inhibitors, natural active compounds, gene or RNA intervention strategies, and novel local delivery systems, can alleviate cartilage degeneration and joint inflammation to varying degrees in experimental OA models

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Vanderah TW (Editor)

95 investigated the post-infection transcript dynamics of a field resistant line and of a susceptible line