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Artificial Intelligence (AI) shows promise in DILI prediction using molecular representations and there is a growing interest in utilizing 2D molecular images for enhanced performance

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Mice in CLP+sh-PHLDA1 and CLP+sh-NC groups were treated with sh-PHLDA1 (AmyJet Scientific, Wuhan, Hubei, China) and sh-NC, respectively, by tail vein injection (1 mg/kg body weight)