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B-017 inhibits apoptotic and necrotic signalling pathways in human cells To gain insight into the inhibitory effects of B-017, we examined its impact on cell death signalling in several mouse and human cell lines

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doi: 10.3390/nu10050560 47 XuKChenZCuiYQinCHeYSongX

High-frequency developmental abnormalities in p53-deficient mice

These irregularities lead to energy failure characterized by decreased ATP production and an increase in lactate concentration, resulting in systemic acidosis