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All research must be conducted under appropriate ethical oversight and regulatory compliance with institutional review board approval where applicable

Receptor sensitisation: Some research suggests that alternating between different secretagogue mechanisms may prevent receptor downregulation compared to chronic stimulation of a single pathway

As such, it might not be wise to incorporate too many objectives into one trial

Biomed Res Int 2016:1575130

Myofascial release is often combined with nighttime bracing, temporary activity reduction, controlled stretching, and rest from the activities that repeatedly aggravate the hand