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In clear cell renal cell carcinoma (ccRCC), elevated expression of PDK2 or PDK3 is associated with increased T-cell infiltration, accompanied by an increased proportion of exhausted CD8 T cells [170]

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Furthermore, labeling a drug as an idiosyncratic, intrinsic or indirect hepatotoxin is not always straightforward

Moreover, Emir et al

The safety and immunogenicity of two Zika virus mRNA vaccine candidates in healthy flavivirus baseline seropositive and seronegative adults: the results of two randomised, placebo-controlled, dose-ranging, phase 1 clinical trials