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Zafar A, Javed S, Akram N, Naqvi SAR

Invest 125 , 35193531 (2015)

These findings align with recent studies on the interaction between tumor metabolism and the immune microenvironment ( Moreover, immune function analysis revealed that elevated glutathione metabolism correlated with a decline in multiple immune functions, including antigen presentation, T cell activation, effector immune responses, and cytokine signaling

NMDA receptors containing GluN2B exacerbate NMDA-induced excitotoxicity

This process results in less toxic and more water-soluble molecules, which are then recognized and transferred across membranes for excretion or sequestration by ATP-dependent membrane pumps