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Abstract Cachexia is a devastating, multifactorial and often irreversible systemic syndrome characterized by substantial weight loss (mainly of skeletal muscle and adipose tissue) that occurs in around 5080% of patients with cancer

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Flavonoids are instrumental in providing significant antioxidant and free radical-scavenging capabilities, whereas ginkgolides and bilobalide are acknowledged for their neuroprotective, anti-apoptotic, and anti-inflammatory properties