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The phrase leaky gut syndrome is interesting, since its not a true medical term, yet the social media hive mind seems to constantly mention it, creating some confusion

Bypasses Gut Absorption Issues: Because it goes directly into the bloodstream, pets with damaged intestinal lining still get the full benefit without depending on gut absorption

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Langberg et al (125) confirmed that IGF-1 directly stimulates collagen synthesis in human connective tissue by measuring tendon tissue changes with stable isotopes and evaluating collagen synthesis around the tendon sheath using micro dialysis