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Symptoms of vitamin B-12 deficiency include: Fatigue Difficulty concentrating Decreased mood Loss of appetite Poor memory Constipation Higher-risk groups for vitamin B-12 deficiency include people with intestinal disorders such as Crohns or Celiac disease, as well as those who suffer from muscular degeneration, Lou Gehrigs disease or diabetes

Eisert WS, Mendelsohn ML, 299-309, 1984

A number of commercially available gene panels, from companies such as Blueprint Genetics, Fulgent and GHC Genetics now offer a conclusive genetic diagnosis [41,42,43]

The three projects underway in the Lipkin lab demonstrate just how important these centers are

Another illustrative example goes for rice