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Figure 6 3.2.3 Microbial markers and therapeutic correlates A cross-sectional study has found that taking atypical antipsychotics (AAPs) led to an increase in a group of gut bacteria called Lachnospiraceae and a decrease in Akkermansia, which is often linked to gut health (Flowers et al., 2017)

For instance, the narrow therapeutic index of colchicine necessitates cautious dosing to prevent toxicity, while uricase therapies (e.g., pegloticase) are challenged by immunogenicity and instability (Yang Y

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The specific activity was calculated from the final protein concentration (1.3 nM g protein -1 min -1 ) in the reaction mixture

Compressing this acute phase provides meaningful quality of life benefit even if total recovery time only shortens moderately