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During slow-wave sleep: The brain reduces sympathetic nervous system output Cortisol secretion drops to its 24-hour nadir Growth hormone pulses the body's primary anabolic and lipolytic signal are highest Insulin sensitivity in peripheral tissues improves DSIP acts upstream of all these processes

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[PubMed] [Google Scholar] Jones T.W., Gerdes R.G., Ormstad K., Orrenius S