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In regions such as the AsiaPacific, where shellfish consumption is high, shellfish allergy is not only more prevalent and clinically significant, but symptoms may also develop at an earlier age compared to Western countries [9, 10]

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In the early stages of DAMD, the basal lamina of the RPE begins to thicken, generating basal lamina deposits (BLamD) and disrupting RPE interactions with the choroid [28]