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These components are believed to increase the levels of GABA in the brain, a neurotransmitter that helps regulate nerve impulses and promote relaxation

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Addressing challenges such as drug resistance, targeting GBM stem cells, and crossing the bloodbrain barrier is essential for improving treatment efficacy

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On the contrary, in anemic conditions where the number of circulating RBCs is decreased without concomitant hemolysis, a decrease of RBC-dependent scavenging of NO may instead increase systemic NO bioavailability and cause vasodilation, increased flow, and may affect cardiovascular hemodynamics (140)

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