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A potential future avenue includes long-acting analogues of LEAP2, a native antagonist of the ghrelin receptor, which may reduce food intake by attenuating ghrelin-mediated orexigenic and lipogenic signaling

A 2011 study investigated the potential lipotropic effects of certain plant products in rats and found the following may have weight loss benefits: choline betaine myoinositol methionine carnitine magnesium niacin pantothenate folates Other substances in plant foods such as fatty acids, fiber, and flavonoids may also have lipotropic effects

But these numbers arent the same for everyone

doi: 10.1053/j.gastro.2006.02.022 356 GaultLMRitchieCWRobiesonWZPritchettYOthmanAALenzRA

So, innovation clusters at the lighter, lower-risk end of innovation, while the conditions that actually kill and disable women, and moments like the postnatal cliff, stay under-served