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WADA Prohibition: MOTS-c is currently prohibited by the World Anti-Doping Agency (WADA) under the category of AMPK Activators and metabolic modulators

In subsequent studies, it was reported that GPx-1 could also protect against cell death in response to cytotoxic drugs, such as doxorubicin, and in response to direct ligand-mediated apoptosis, by ligand for CD95 receptor (CD95L) (142, 143)