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For this reason, the penumbra represents the most therapeutically relevant target in ischemic stroke research

The research findings indicated that NAC conferred neuroprotection via two separate compensatory mechanisms: (1) the decrease in -synuclein overexpression, and (2) the modification of NFB translocation from the nucleus to the cytoplasm, thereby preventing the activation of subsequent pro-inflammatory genes

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As a common beneficial intestinal bacteria, Rikenellaceae could degrade plant-derived polysaccharides and alleviate the colitis by mediating T-regulatory cell differentiation (60)