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FIGURE 3 On the other, hyperglycemia also induces metabolic alterations, resulting in the disturbance of protein, fat, and carbohydrate metabolism

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Double knockout of MLKL and caspase-8 nearly abolishes IL-1 release and delays cell death, highlighting a multi-layered inflammasomecell death axis that ensures sustained inflammatory signaling

In 1978 and 1990, the first intracellular delivery of mRNA and its delivery in murine models were achieved, respectively [5, 6, 9]

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