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The reaction was incubated 1 h at room temperature, diluted with 20 mM Tris pH 8.0, diafiltrated, rediluted and the protein digested by trypsinization for 3 h

To explore the molecular basis for these potential changes, we cross-referenced 1178 upregulated DEGs from Dmp1-Cre

The best explanation is that xenobiotics hit the gland directly via the arterial route, whereas ingested toxicants first encounter the liver which is best equipped to deal with RXS, via its huge complement of GSH and GST (21, 170)

National Institutes of Health, Bethesda, USA) by measuring the mean pixel intensity within the selected region of interest in 16-bit images and is expressed in arbitrary units (AUs) in Fig

It is known that high doses of APAP are toxic for two reasons