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doi: 10.1523/JNEUROSCI.3817-03.2004 77 KumarV

The cGAS-cGAMP-STING pathway connects DNA damage to inflammation, senescence, and cancer

Phase 2 metabolites can also be shunted to lactate for NAD + regeneration, used to synthesize alanine and the branched chain amino acids, or to acetyl-CoA for lipid synthesis