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18 For example, in one study, researchers discovered that when GSH is depleted in the hippocampus regions of an elderly person the healthy brain suffers mild cognitive impairment, which is known to be present in the earlier stages of AD

5,8 Our data demonstrate that of the 5 prosurvival BCL-2 family members, only BCL-2 mRNA levels consistently anti-correlate with the AR-A in all clinical datasets we have interrogated and only BCL-2 is consistently induced by castration (e.g., in 3 of the 4 xenograft AI models) (Fig

10.3109/21691401.2013.794358 13 ChenX.WangQ.ShaoM.MaL.GuoD.WuY.et al (2019)

& Masarik, M

This results in hyperthyroidism and symptoms of thyrotoxicosis including: weight loss diarrhoea increased appetite flushing irritability tiredness palpitations (increased heart rate which can be felt by the patient) poor sleep increased sweating a tremor heat intolerance (feeling excessively hot even though others may find it cold)