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The TEM image (Fig

This results in B12 malabsorption, deficiency, and megaloblastic (abnormally large and dysfunctional) RBCs in many cases

The JAK family (JAK1, JAK2, JAK3, TYK2) binds non-covalently to cytokine receptors, while STATs, as JAK substrates, couple with the tyrosine phosphorylation signaling pathway [117]