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10.1007/s11011-014-9549-9 14 GrynkiewiczG.PoenieM.TsienR

Some reviews have called DSIP a still unresolved riddle, meaning the evidence is promising but not definitive

However, recent evidence showed that IP 3 R1 and IP 3 R3 are also present in astrocytes and participate in Ca 2+ -mediated signaling, especially in astrocytic processes (Sherwood et al., 2017, 2021b)