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By selectively inhibiting NNMT an enzyme central to energy regulation and fat metabolism this compound has demonstrated, in preclinical studies, the capacity to elevate intracellular NAD and SAM levels, suppress lipid accumulation in adipocytes, and reduce white adipose tissue mass in diet-induced obese mouse models

J Biol Chem 285:4152532

To view a copy of this licence, visit About this article Cite this article Scherschel, M., Niemeier, JO., Jacobs, L.J.H.C

ELISA) and binding assays MaxiSorpsurface has a high affinity to molecules with mixed hydrophilic/hydrophobic domains

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