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doi: 10.1126/science.1061663, PMID: [DOI] [PubMed] [Google Scholar] Ma Q., Zhao Z., Sagare A

Where indicated, confocal live imaging over 16 h was performed to analyze the incorporation of immune cells into the epithelial layers

The p38 MAPK/STAT6 pathway is involved in ferroptosis-induced VEGFA and IL8 induction We further investigated the mechanism of ferroptosis-induced VEGFA and IL8 upregulation in ESCs

J Cell Biol 217:19852004 Sun H, Zhang J, Xin S, Jiang M, Zhang J, Li Z, Cao Q, Lou H (2019) Cul4-Ddb1 ubiquitin ligases facilitate DNA replication-coupled sister chromatid cohesion through regulation of cohesin acetyltransferase Esco2

The imbalance in calcium and iron depletes and alters the glutathione (GSH) enzyme responsible for the antioxidant defense against xenobiotics (e.g., external chemicals, drugs, pesticides, carcinogens) for detoxification by making these compounds more soluble