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measured the urinary HS concentration, which may reflect renal glycocalyx degradation, and found that HS was the only glycosaminoglycan that was significantly associated with mortality (hyaluronic acid and chondroitin sulfate were not) and that patients who died of sepsis had significantly higher mean HA concentrations at the start of the study than survivors (112)

The buildup of specific lipid species, especially Diacylglycerol (DAGs) and ceramides, causes oxidative damage through ROS generation

doi: 10.1017/S1368980014001244, 8

MMA is a myelin destabiliser and can affect normal myelin formation

10.1080/10408398.2023.2229433 112 WenK.-C.FanP.-C.TsaiS.-Y.ShihI.-C.ChiangH.-M