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It is primarily used for growth hormone deficiency (GHD) and as an anti-aging or performance-enhancing therapy due to its ability to promote muscle growth, fat loss, and improved recovery

Patients already on GLP-1 therapy for metabolic syndrome or obesity may still benefit from tesamorelin if a GH-axis component is contributing to their visceral fat though combination use requires careful clinical evaluation

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According to a 2023 review in Cureus, the bacteria can transition from their active, motile spirochete form into dormant, drug-tolerant round bodies, or aggregate into protective biofilm-like structures