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Once freed, vitamin B12 initially binds to haptocorrin (R-protein) in the stomach before being transferred to intrinsic factor, a glycoprotein secreted by parietal cells in the stomach lining

Start at the lower end of the dosing range to assess individual response

People with vitamin B12 deficiency could have a wide range of symptoms including tiredness, stress, loss of appetite, low moods, feeling light-headed and a pale complexion

Most side effects diminish significantly after the first few months, but if they persist and significantly impact quality of life, alternative medications or dose modifications should be discussed

Interactions to Avoid Vitamins, minerals, and supplements can interact, affecting absorption and effectiveness