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Yes, both are generally safe under medical supervision

BPC 157+L-NAME+L-arginine-rats BPC 157+L-NAME+L-arginine-rats after amputation only, or heparin or warfarin administration, exhibited a consistent attenuation of thrombocytopenia, along with lesser bleeding time and/or amount, than corresponding controls

While research is still limited on the link between vitamin B12 and weight gain, most evidence suggests that the vitamin itself wont cause you to put on pounds, but a deficiency may