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At the end of experimental period, mice were euthanized by decapitation under ether anesthesia

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Thus, near-to-invariably, these approaches would study SNPs known or expected to influence cellular or organismal processes linked to CDDP sensitivity, such as CDDP extrusion (e.g., SNPs affecting ABCC2), DNA damage-elicited signal transduction (e.g., SNPs affecting ERCC1), apoptosis (e.g., SNPs affecting caspases) or immune responses (e.g., SNPs affecting cytokines or their receptors)

Thus, it is extremely beneficial in several oxidative-stress-associated conditions such as ischemia-reperfusion (cardiovascular disease or strokes) or radiation injury

The study found that glutathione concentration, peroxide concentration, and incubation time significantly influenced GPx activity measurement